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科研文章

        建院至今我院在《Nature Medicine》、《Circulation》、《Circulation Research》、《The Journal of Clinical Investigation》等雜志共發表SCI收錄文章629篇,其中影響因子大于10的5篇,5-10的91篇(截止2016.12)。
近幾年發表影響因子大于5的第一作者單位文章:
論文題目/通訊作者(中文)/雜志名稱/國際標準刊號ISSN /發表年份/卷/期/頁碼/影響因子

HIV Tat protein inhibits hERG K+ channels: a potential mechanism of HIV infection induced LQTs. 董德利 Journal of Molecular and Cellular Cardiology 0022-2828 2011 51 5 876-80 5.499
Overexpression of M3 Muscarinic Receptor Is a Novel
Strategy for Preventing Sudden Cardiac Death in Transgenic
Mice 楊寶峰  高旭 molecular medicine 1076-1551 2011 1 7   1 1 - 1 2  1 1 7 9 - 1 1 8 7 5.908
The negative inotropic effects of homocysteine were prevented by matrine via the regulating intracellular calcium level  呂延杰 INTERNATIONAL JOURNAL OF CARDIOLOGY   0167-5273 2011 150 1 113-115    6.802
Arrhythmogenic potential of oxidative stress in atrial myocytes  呂延杰 INTERNATIONAL JOURNAL OF CARDIOLOGY   0167-5273 2011 150 2 219-221 6.802
Pseudogene Recoding Revealed from Proteomic Analysis of
Salmonella Serovars 馮曄 J. Proteome Res 1535-3893 2012 11 3 1715?1719 5.113
Mild hypoxia-induced cardiomyocyte hypertrophy via up-regulation of HIF-1α-mediated TRPC signalling.  楊寶峰  Journal of Cellular and Molecular Medicine  1582-1838 2012 16 9 2022-2034 5.228
Insulin-like growth factor-1(IGF-1) inhibits the basolateral Cl channels in the thick ascending limb of the rat kidney 谷瑞民 BBA - Molecular Cell Research 0167-4889 2012 1823 7 1163-1169 5.538
Stimulation of Ca2+ -sensing receptor inhibits the basolateral 50-pS K channels in the thick ascending limb of rat kidney 谷瑞民 BBA - Molecular Cell Research 0167-4889 2012 1823 2 273-281 5.538
Activation of JNK/c-Jun pathway is required for the cell proliferation, survival and angiogenesis by epoxyeicosatrienoic acids in pulmonary arterial endothelial cells 朱大嶺 Journal of Lipid Research   0022-2275 2012 53 6 1093-1105 5.559
 Arsenic-induced interstitial myocardial fibrosis reveals a new insight into drug-induced long QT syndrome. 楊寶峰 Cardiovascular Research 0008-6363 2012 96 1 90-98 6.064
Overexpression of microRNA-1 impairs cardiac contractile function by damaging sarcomere assembly 艾靜,楊寶峰 Cardiovascular research 0008-6363 2012 95 3 385-393 6.064
The microRNA-328 regulates hypoxic pulmonary hypertension by targeting at insulin growth factor 1 receptor and L-type calcium channel-α1C 朱大嶺 Hypertension 0194-911X 2012 59 5 1006-1013 6.207
Response to Promotion of Apoptosis Does Not Necessarily Mean Inhibition of Remodeling  朱大嶺 Hypertension 0194-911X 2012 60 1 e4 6.207
Bone marrow-derived mesenchymal stem cells protected rat cardiomyocytes from premature senescence. 呂延杰 international journal of cardiology 0167-5273 2012 154 2 180-2 7.078
Elevated plasma microRNA-1 predicts heart failure after acute myocardial infarction 艾靜,楊寶峰 International journal of cardiology 0167-5273 2012   online   7.078
microRNA-124 regulates cardiac differentiation in bone marrow-derived mesenchymal stem cells via targeting STAT3 signaling 呂延杰 Stem Cells 1066-5099 2012 30 8 1748-1755 7.781
MicroRNA-101 inhibited postinfarct cardiac fibrosis and improved left ventricular compliance via the FBJ osteosarcoma oncogene/transforming growth factor-β1 pathway. 楊寶峰 Circulation 0009-7322 2012 126 7 840-850 14.739
Elevated plasma microRNA-1 predicts heart failure after acute myocardial infarction 艾靜,楊寶峰 International Journal of Cardiology  0167-5273 2013 166 1 259-60 5.509
15-Lipoxygenase Promotes Chronic Hypoxia–Induced Pulmonary Artery Inflammation via Positive InteractionWith Nuclear Factor-κB 朱大嶺 Arterioscler Thromb Vasc Biol 1079-5642 2013 33   971-979 6.338
Bone morphogenetic protein-4 mediates cardiac hypertrophy, apoptosis, and fibrosis in experimentally pathological cardiac hypertrophy. 董德利 Hypertension. 0194-911X (Print)
1524-4563 (Electronic) 2013 61   352-60 6.873
Angiotension II Stimulates Basolateral 10-pS Cl channels in the Thick Ascending Limb 谷瑞民 HYPERTENSION 0194-911X 2013 61 6 1211-1217 6.873
MicroRNA-195 protects against dementia induced by chronic brain hypoperfusion via its anti-amyloidogenic effect in rats 艾靜,楊寶峰 The journal of neuroscience  0270-6474 2013 33 9 3989-4001  6.908
 Suppression of AKT expression by miR-153 produced anti-tumor activity in lung cancer 單宏麗 international journal of cancer 1097-0215 2014       5.007
Calcineurin suppresses AMPK-dependent cytoprotective autophagy in cardiomyocytes under oxidative stress 楊寶峰,單宏麗 Cell Death and Disease 2041-4889 2014 5   e997 5.177
Integrated Analyses Identify the Involvement of MicroRNA-26a in Epithelial-Mesenchymal Transition during Idiopathic Pulmonary Fibrosis 張勇、呂延杰 Cell Death and Disease 2041-4889 2014 5   e1238 5.177
MicroRNA-30d regulates cardiomyocyte pyroptosis by directly targeting foxo3a in diabetic cardiomyopathy 艾靜,楊寶峰 Cell Death and Disease 2041-4889 2014 5 網絡版 e1479 5.177
MicroRNA-23a mediates mitochondrial compromise in estrogen deficiency-induced concentric remodeling via targeting PGC-1α 張勇、單宏麗 journal of molecular and cellular cardiology 0022-2828 2014 75   1-11 5.218
β-Blocker carvedilol protects cardiomyocytes against oxidative stress-induced apoptosis by up-regulating miR-133 expression. 呂延杰 Journal of Molecular and Cellular Cardiology 0022-2828 2014 75 1 111-121 5.218
Gusongning reduced the susceptibility of orchidectomized rats to arrhythmias in infarcted myocardium. 呂延杰,楊寶峰 International Journal of Cardiology 0167-5273 2014 172 1 e162-4 6.175
Expression profile of long non-coding RNAs in a mouse model of cardiac hypertrophy.  李柏巖,喬國芬 International Journal of Cardiology 0167-5273 2014 177 1 73-5 6.175
Hyperpolarization-activated current-mediated slow afterhyperpolarization in myelinated Ah-type of baroreceptor neurons isolated from adult female rats 李柏巖,喬國芬 Int J Cardiol  0167-5273 2014 172 1 e106-108 6.175
Electrophysiological Remodeling of Linopirdine on Neuroexcitability of Myelinated A-type Baroreceptor Neurons in Rats  李柏巖,喬國芬 Int J Cardiol  0167-5273 2014 173 3 528-530 6.175
Fine tuning of calcium on membrane potential of baroreceptor neurons in rats 李柏巖,陳漢英,喬國芬 Int J Cardiol  0167-5273 2014 174 3 883-887 6.175
Alternation of cardiac Ik1 and Ito from FKBP12.6 transgenic mouse heart and potential impact of cardiac hypertrophy 楊寶峰,單宏麗 Int J Cardiol  0167-5273 2014 176 3 1017-1025 6.175
MicroRNA-328 as A Regulator of Cardiac hypertrophy 單宏麗,杜智敏 international journal of cardiology 0167-5273 2014 173 2 268-76 6.175
Microrna regulation and cardiac calcium signaling: Role in cardiac disease and therapeutic potential. 李柏巖 Circulation Research 0009-7330 2014 114 4 689-705 11.089
Hyperpolarization-activated current-mediated slow afterhyperpolarization in myelinated Ah-type of baroreceptor neurons isolated from adult female rats 李柏巖 International Journal of Cardiology 0167-5273 2014 170   DOI:10.1016/j.ijcard.2013.12.127 5.509
miR-183 regulates autophagy and apoptosis in colorectal cancer through targeting of UVRAG 單宏麗 Oncotarget 1949-2553 2015 7 4 4735-4745 5.008
Na+-induced Ca2+ influx through reverse mode of Na+-Ca2+ exchanger in mouse ventricular cardiomyocyte. 艾靜 Oncotarget 1949-2553 2015 6 27 23272-23280 6.359
Vasopressin-induced stimulation of the Na+-activated K+ channels is responsible for maintaining the basolateral K(+)conductance of the thick ascending limb(TAL)in EAST/SeSAME syndrome 谷瑞民,王文輝 Biochimicaet Biophysica Acta  0925-4439 2015 1852 1852(2015) 2554-2562 5.185
Suppression of AKT expression by miR-153 produced anti-tumor activity in lung cancer. 楊寶峰 International journal of cancer 1097-0215 2015 136 6 1333-40 5.085
MicroRNA-26a prevents endothelial cell apoptosis by directly targeting TRPC6 in the setting of atherosclerosis 呂延杰 SCIENTIFIC REPORTS 2045-2322 2015 5 ### 1—10 5.578
Bone marrow mesenchymal stem cell transplantation retards the natural senescence of rat hearts. 李柏巖 Stem Cells Translational Medicine 2157-6564 2015 172 15 494-502 5.709
MicroRNA - 9 induces defective trafficking of Nav1.1 and Nav1.2 by targeting Navβ2 protein coding region in rat with chronic brain hypoperfusion 潘振偉 MOLECULAR NEURODEGENERATION 1750-1326 2015 10   1-36 6.563
Neuropeptide Y-Mediated Sex- and Afferent-Specific Neurotransmissions Contribute to Sexual Dimorphism of Baroreflex Afferent Function 李柏巖 Oncotarget 1949-2553 2016 7 40 66135-66148 5.008
Physiological and pathological implications of 5-hydroxymethylcytosine in diseases 蔡本志 Oncotarget 1949-2553 2016 7 30 48813-48831 5.008
GDF11/BMP11 activates both smad1/5/8 and smad2/3 signals but shows no significant effect on proliferation and migration of human umbilical vein endothelial cells. 董德利 Oncotarget 1949-2553 (Electronic);1949-2553 (Linking) 2016 7 11 12063-74. 5.008
MT2-MMP induces proteolysis and leads to EMT in carcinomas. 呂昌蓮,周凌云 Oncotarget 1949-2553 2016 7 30 48193-48205 5.008
Polymorphisms in the CHIT1 gene: Associations with colorectalcancer 劉樹林 Oncotarget 1949-2553 2016 7 26 39572-39581 5.008
Knockdown of microRNA-195 contributes to protein phosphatase-2A inactivation in rats with chronic brain hypoperfusion 艾靜 Neurobiology of Aging. 0197-4580 2016 45   76-87 5.153
Reciprocal Changes of Circulating Long Non-Coding RNAs ZFAS1 and CDR1AS Predict Acute Myocardial Infarction. 呂延杰 Scientific Reports 2045-2322 2016 1 6 22384 5.228
FGF21 ameliorates the neurocontrol of blood pressure in the high fructose-drinking rats 李柏巖 Scitific Reports  2045-2322 2016 6   29582 5.228
Deletion of interleukin-6 alleviated interstitial fibrosis in streptozotocin-induced diabetic cardiomyopathy of mice through affecting TGFβ1 and miR-29 pathways 潘振偉 Scientific reports 2045-2322 2016 6   23010 5.228
The anti-hyperglycemic efficacy of a lipid-lowering drug Daming capsule and the underlying signaling mechanisms in a rat model of diabetes mellitus 張勇、楊寶峰 Scientific Reports 2045-2322 2016 6 6 34284 5.228
Endothelial to mesenchymal transition contributes to arsenictrioxide-induced cardiac fibrosis 張勇、楊寶峰 Scientific Reports 2045-2322 2016 6 6 33787 5.228
SOX7 co-regulates Wnt/β-catenin signaling with Axin-2: both expressed at low levels in breast cancer 劉樹林 Scientific Reports 2045-2322 2016 6   26136 5.228
Live attenuated Salmonella displaying HIV-1 10E8 epitope on fimbriae: systemic and mucosal immune responses in BALB/c mice by mucosal administration 王福祥,劉樹林 Scientific Reports 2045-2322 2016 6   29556 5.228
Downregulation of miR-522 suppresses proliferation and metastasis of non-small cell lung cancer cells by directly targeting DENN/MADD domain containing 2D 張勇、張臨友 Scientific Reports 2045-2322 2016 6 6 19346 5.228
Mitochondrial uncoupler carbonyl cyanide m-chlorophenylhydrazone induces vasorelaxation without involving KATP channel activation in smooth muscle cells of arteries. 董德利 British journal of pharmacology. 0007-1188 (Print);1476-5381 (Electronic);0007-1188 (Linking) 2016 173 21 3145-3158 5.259
Unique Expression of Angiotensin Type-2 Receptors in Low-Threshold and Sex-Specific Distribution of Myelinated Ah-Type Baroreceptor Neurons and Contribution to Sexual Dimorphism in Neurocontrol of Circulation  李柏巖 Hypertension  0194-911X 2016 67   783-791 6.249
Mitochondrial Fission of Smooth Muscle Cells Is Involved in Artery Constriction. 董德利 Hypertension 0194-911X (Print);1524-4563 (Electronic);0194-911X (Linking) 2016 68 5 1245-1254. 6.350
Long non-coding RNA H19 mediates melatonin inhibition of premature senescence of c-kit+ cardiac progenitor cells by promoting miR-675 楊寶峰 Journal of Pineal Research 0742-3098 2016 61   82–95 9.314


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